Combining over-the-counter medications can sometimes lead to unforeseen effects. Even though both Sudafed and Ibuprofen are commonly used to treat symptoms, it's important to be cognizant of potential interactions. https://www.sistempompa.com/Medical-Technology/sulfamethoxazole-trimethoprim-a-comprehensive-review-of-its-pharmacology--clinical-applications--and-adverse-effects/