The design of multifunctional magnetic nanoparticles (NPs) that can generate and monitor heat release in real-time during thermal therapy is a major challenge in nanomedicine. In this work. a trimodal system that combines magnetic hyperthermia (MH). photothermal therapy (PT) and luminescence nano-thermometry (LT) has been set up in a single platform. https://jalyttlers.shop/product-category/satchel/