Abstract Background As a common clinical symptom that often bothers midlife females. migraine is closely associated with perimenopause. Previous studies suggest that one of the most prominent triggers is the sudden decline of estrogen during perimenopausal period. Hormone replacement therapy (HRT) is widely used to prevent this suffering in perimenopausal women. https://www.marketingjeunesse.com/product-category/pro-longer-shampoo/